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- American patients pay up to three times more for prescription drugs than those in other developed nations due to 'global freeloading'.
- An Executive Order, 'Delivering Most-Favored-Nation Prescription Drug Pricing to American Patients,' was signed on May 12, 2025.
- Pharmaceutical manufacturers are called upon to extend MFN pricing to Medicaid for all existing drugs and to Medicare, Medicaid, and commercial payers for newly-launched drugs.
- Manufacturers are required to return increased revenues earned abroad to American patients and taxpayers.
- Manufacturers are urged to participate in Direct-to-Consumer and/or Direct-to-Business models for MFN pricing.
- The Administration will deploy 'every tool in our arsenal' if manufacturers do not comply.
- Binding commitments are expected from manufacturers by September 29, 2025.
- Secretary Kennedy and Administrator Oz are part of the implementation team for these policies.